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Post by Admin on Jun 24, 2012 7:38:22 GMT
This seems to be something that affects a lot of women yet why don’t doctors talk about it more? I have read that it affects about 20% of women, and it’s often given as the reason why a lot of women stop using HRT. Sure there’s a lot of information on google, if you know what to look for, but I’d never even heard of it until a few months ago, so how could I ask about it if I didn’t know about it? I ended up finding out that it was my problem quite by accident. The story would always be the same. I’d start on a new HRT, really hopeful that this would be the one. The first couple of weeks would be good, then the depression, anxiety, insomnia and suicidal thoughts would return. Seeing as every HRT I tried would always be the continuous kind I was never on just oestrogen alone, so I never realised that the progesterone was the problem. However, by accident one day the chemist dispensed sequi patches to me (2 weeks oestrogen/2 weeks oestrogen and progesterone) and it became very apparent very quickly that when I was on the progesterone I felt like crap. Now I have a very good GP, but even she never mentioned that my problem could be related to progesterone, even though I was sitting in her office on average every 2-3 weeks, literally crying from despair and frustration. She was about to refer me to a gynaecologist, so had that happened I hope he/she would have had the sense to pinpoint it as my problem. Although I don’t know what their remedy would have been. In Australia, for some reason, we don’t have a bio-identical progesterone available for menopause (Utrogestan) like practically every other country does. We do have one for pregnancy, but it's not licensed for menopause. I’m not sure why that is. Australia leads the world in so many other areas of women’s health research like breast cancer, and the HPV vaccine was invented in Australia, but for some reason no one's interested in helping menopausal women with this problem. I even sent an email to the Australian Menopause Society, but they never even bothered to answer me. Anyway, through our very own Candy, I found out about a European website where you can buy it online. I discussed it with my doctor, and she is perfectly fine with me getting it that way. Her attitude has always been “you do what works for you”. She is also interested to hear how I go, because I'm sure she has other patients like me. Of course ethics will prevent her from telling her patients to buy medication online, but she may be able to prescribe the pregnancy progesterone pessary. It is a lot more expensive than buying the Utrogestan online, so I wasn't interested in getting it that way, although if I was desperate I would pay for it. So for anyone else who is unable to get Utrogestan from their doctor, or who wants to buy it online, here is the website that Candy and I use. It’s a perfectly legitimate website and the price is also very reasonable. I can get 30 capsules for about AU$30 which includes the cost of the prescription and postage. Just type Utrogestan into the search field, and away you go. goldpharma.com/?show=login&lang=ENGLISHI know we have a number of members who have done a lot of research into its use, so I thought this would be a good place to discuss all things Utrogestan. There are numerous way women use it – vaginally, orally, continuous, 2-3 monthly cycles. It’s all trial and error really. You just need to find a way that suits you. I personally am currently using a 100mg capsule vaginally every second night as a continuous method (no periods). I’m still in the settling in period, where I’m getting some break-through bleeding, but hopefully that will settle in time. Other ladies use 200mg for 10-12 days every 2-3 months. This gives them a period a few days after ceasing the Utrogestan. Others use 100mg for 10-12 days every month, and that gives them a monthly bleed. These ladies either use it orally or vaginally.
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Post by jacksfullofaces on Jun 26, 2012 18:08:43 GMT
I love Utrogestan but norithisterone is disgusting. Dydrogesterone isn't a bad progestin but in the UK it was discontinued unless combined with a patch. Jacks
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Post by Admin on Jun 27, 2012 8:28:33 GMT
I think I must have been intolerant to most synthetics, because it didn't matter what HRT I was given, I would still have the same reaction. Although the first HRT I was on was Livial which contains tibolone. I was okay on that one for 9 months, but it ended up not being strong enough.
I've been on Utro now for exactly a month this Monday just gone, and I've had 2 break through bleeds, but nothing for the last couple of weeks, even though I stopping using it last week for a few days. I thought that would cause a bleed for sure, but so far so good, so hopefully I'm settling into it now.
I also find that it give me a really nice "sedated" feeling when I use it. Bliss.....lol...
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Post by Deleted on Jun 27, 2012 15:16:07 GMT
I am still trying to pinpoint if I sleep better on the Utro nights - I think I do. Last night was one and I don't even remember dreaming so it was a decent sleep (bit unusual but not complaining). Good news Robyn that so far the breakthrough bleeding has subsided. I was ready to throw in the towel but glad I persevered.
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Post by Jenny Wren on Jun 27, 2012 19:38:40 GMT
My first progestin was via the Mirena coil - levonogestrel. I had five and a half months of hell with it. Family planning doctor kept telling me it couldn't possibly be causing all the symptoms I had as it delivered locally only. I think it is now generally accepted that for some women it delivers systemically.
Evorel Sequi - norethisterone = migraines, depression, anxiety.
Fem-Seven conti - levo again, lasted three days before I started to climb the walls.
Utrogestan every other night 100mg, was lovely to start with, morning terrors gone, anxiety very much reduced and was sleeping really well.
Unfortunately after two months on that regime it must have built up in my system because I turned into a total zombie, depression, sleeping all day/night and migraines. I was really disappointed as Utro helped so much with the anxiety.
Now about to try Utrogestan 3 monthly cycle.
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Post by Admin on Jun 27, 2012 22:29:09 GMT
It's shame the alternative night Utro didn't suit you. I'm still to find out if it will suit me. I'm hoping so, but if it doesn't I will go to the 2 or 3 monthly cycle.
Just thinking out loud here - has there been any studies done on taking Utro every third night? I wonder if that might be another alternative?
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Post by jacksfullofaces on Jun 28, 2012 13:29:17 GMT
Juat a thought many ladies have difficulty with progesterone regime. You can always have a scan done yearly to check your lining. If the lining is okay then your levels are fine. Sometimes I think that there is overkill with progestin/progesterone caused by fear of endometrial cancer. If anyone is going to do progresterone every third night it might be an idea to arrange a scan as a base line. Jacks
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Post by Gelis on Jun 28, 2012 16:50:53 GMT
Good to see this subject resurrected on this forum!
I have always had the opposite problem - progesterone levels too low; that was what needed supplementing more than the oestrogen. I took Duphaston (dydogesterone) alone for several years, and then had it combined with oestrogen in Femoston 2/20 which suited me very well. As I said in my intro, I now don't have HRT at all, and it took quite a while to adjust to being without the extra progesterone.
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Post by Jenny Wren on Jun 28, 2012 19:10:05 GMT
Fingers crossed for you and the Utro Robyn - I think it's got lots going for it. Apart from helping initially with anxiety and sleep it also brought to an end the constipation I've had for several years. I was using it by V route.
I did wonder about taking it every third night too, but I felt so ill and overloaded with it after two months I just had to stop it completely.
Jacks - I've wondered about the overkill too, and as you say, if you have regular scans any build up can be picked up quickly and dealt with.
Gelis - hope you don't mind me asking but what were your symptoms of low progesterone? I'm sure I would benefit from a very small amount, just not the levels I was taking it at.
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Post by Gelis on Jun 28, 2012 19:27:38 GMT
Hi Jenny
My main symptoms were extremely erratic periods which, since we were hoping to start a family, were causing problems, to put it mildly. I also suffered from horrendous pms. I was lucky in that my GP put me on Duphaston (when I was about 34) and it suited straight away. It was only when I was in my early 40s that it seemed to stop working (and the mood swings became intolerable) that I wondered if something else was going on. My GP wasn't convinced that I was peri, but sent me to a consultant who confirmed it and put me straight onto Femoston 2/20 - the same amount of dydrogesterone with added oestrogen.
Hope you can find the "right" amount for you! I know I was lucky with the HRT - I had a short spell on Premarin when Femoston was discontinued, and it was awful. My GP then prescribed me the two hormones separately - back to happiness!
Gxx
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Post by jacksfullofaces on Jun 29, 2012 10:37:07 GMT
Hi Jenny I was using Emerita Progesterone cream but for me it wasn't strong enough. I suffered irritability, headaches, nasty high cramp periods with heavy bleeding and clots. I started on Utrogestan - fortunately it suited me and those symptoms vanished. I did get some brerak through bleeding at first but found I had a Thyroid issue which was the cause. Break through bleeding has now stopped thanks to thyroid medication and I had kept my endometrial lining at 7mm which is fine. The person doing the second scan explained that it is not just thickness which is a concern but what is normal for the individual woman. Jacks
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Post by Jenny Wren on Jun 29, 2012 17:35:32 GMT
Hi Gelis, That's interesting about the Duphaston, I wish my gyne had suggested it for me. When I had terrible PMS he said I could try Danazol, but it would probably cause facial hair and I might have to start shaving . I decided against it. The other thing he suggested was Evening Primrose Oil. I took 3g daily of that for months with no effect what so ever. Quite a while back I was looking for a different progestin for HRT and whilst searching came across Duphaston - only to be told by GP it had been discontinued. Thanks Gelis, I'm sure I'll find something to suit eventually. Great to hear you're back to happiness. Hi Jacks, I can't remember what regime you are on - do you use Utro orally every night, or one of the other regimes? I did give Utro a try orally as I thought it might be less potent than V route but it caused indigestion. I didn't realise that thyroid function could effect other hormones re bleeding - it's all so complicated! Great that you've got it all sorted out and doing well. I've not heard of Emerita - I'll go google it. I'll be seeing the gyne in about a months time so will find out what she intends to do re the scans.
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Post by Jenny Wren on Jun 30, 2012 18:04:37 GMT
Candy - do you know how much and how often your friend takes the Duphaston?
It has crossed my mind to try it. It's very annoying that this product has been taken off the market in the UK as we have so few Progestins to choose from and so many women have problems with the P part of HRT.
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Post by jacksfullofaces on Jun 30, 2012 20:26:29 GMT
Hi Gelis, That's interesting about the Duphaston, I wish my gyne had suggested it for me. When I had terrible PMS he said I could try Danazol, but it would probably cause facial hair and I might have to start shaving . I decided against it. The other thing he suggested was Evening Primrose Oil. I took 3g daily of that for months with no effect what so ever. Quite a while back I was looking for a different progestin for HRT and whilst searching came across Duphaston - only to be told by GP it had been discontinued. Thanks Gelis, I'm sure I'll find something to suit eventually. Great to hear you're back to happiness. Hi Jacks, I can't remember what regime you are on - do you use Utro orally every night, or one of the other regimes? I did give Utro a try orally as I thought it might be less potent than V route but it caused indigestion. I didn't realise that thyroid function could effect other hormones re bleeding - it's all so complicated! Great that you've got it all sorted out and doing well. I've not heard of Emerita - I'll go google it. I'll be seeing the gyne in about a months time so will find out what she intends to do re the scans. hi I take 100mg of Utrogestan every evening orally - it has been a zig zag path getting completely hormonally well but worth the perseverance Jacks
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Post by Admin on Jul 1, 2012 5:28:19 GMT
Thanks Candy. That's all such interesting info for us prog intol ladies. So far I'm still going okay, doing the 100mg on alternate nights. One thing I have noticed though (or maybe imagined) is that on the nights that I use the Utro I sometimes feel that really low down twinge that you get sometimes when a period is on it's way, but nothing comes of it. It's not painful or even annoying. It's just there. So hopefully that's all it will be and won't progess to something more annoying as time goes on. Fingers crossed.
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Post by Admin on Jul 1, 2012 7:33:51 GMT
Interesting. Well so far it's definitely not as bad as cramping, just a twinge. So I hope that doesn't start. Wait and see I guess.
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Post by Jenny Wren on Jul 1, 2012 20:07:59 GMT
Jacks - Thanks, pleased that the zig zag path has straightened out a bit, long may it last!
Candy - I agree with Bellaciao - you should publish!
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Post by Admin on Jul 1, 2012 22:47:55 GMT
Oops - I hadn't thought about it from that angle. I will come up with some new names - I promise...lol....
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Post by Admin on Jul 2, 2012 8:40:07 GMT
Good point. I tried to get rid of the titles and just have the coloured stars, but it didn't like me doing that. So I've dispensed with the lot. If everyone's happy with that I'm happy too.
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Post by jacksfullofaces on Jul 2, 2012 11:54:59 GMT
Candy You sound fine - long live authoritive Jacks
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Post by newbaby1234 on Feb 5, 2013 16:22:55 GMT
Does the three monthly hrt have a name?
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Post by rusalka on Feb 7, 2013 14:57:50 GMT
Wow, so much interesting informations about progesterone! And contradictory too :-) It's bewildering that there are so different opinions about P amongst the doctors. I'm now using a half capsule of Utrogest for 12 days in the cycle vaginal, to see how this will work for my cycle. I think I'm tolerating P better taken vaginal as oral. I only wonder why I had two bleedings ( quite strong) in one cycle- too low P, too high E? Or too much P and too low E? Or it's just normal that even under HRT the bleedings are irregular? Now I'm day 14 and since one week I feel very good, so I wonder if this will stay so also in the second half of the cycle...Before the last bleeding 2 weeks ago PMS was extremely and also anxiety came back. Now I'm 90% anxiety free and also the depressive moods are much better. Hopefully not only till the next PMS...
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Post by rusalka on Mar 23, 2013 16:44:44 GMT
There is one thing what I'm wondering about- I know few ladies who are using the progesterone cream and they feel good again, the symptoms of the menopause are much less and they say P-cream was a life saviour for them. They don't take any estrogen at all. How could this be possible? Do they maybe still have sufficient own estrogen levels? Also my ex gyno wanted to put me only on P-cream, without estrogen, but I felt bad only on P.
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